Shikari® (S-ATT) Anti-Trastuzumab ELISA w/confirmation
TRA-QNS-HH
Enzyme immunoassay for the quantitative determination of antibodies to Trastuzumab (Herceptin®, Herclon®) in serum and plasma with confirmation.
This kit has been especially developed for the quantitative antibodies to Trastuzumab in serum and plasma samples.
Trastuzumab (Herceptin®, Herclon®)was associated to the development of anti-trastuzumab antibodies, even some were reported to be neutralizing, in various percentages of patients during therapy with the drug (Herceptin®, Herclon®). This might lead to severe complications. This kit can be efficiently used for monitoring anti- trastuzumab antibodies during therapy and offers the clinician a tool for decision on possible preventive measures such as possible addition of immunosuppressive drug to reduce anti-trastuzumab antibodies.
All SHIKARI® ELISA kits are suitable for biosimilar work.
All SHIKARI® ELISA kits are produced under ISO 13485 quality system.
Research Use Only (RUO)
For technical inquiry, IFU and other relevant documents please contact techsupport@matriksbiotek.com
| Required Volume (µl) | 20 |
| Total Time (min) | 140 |
| Sample | Serum, plasma |
| Sample Number | 96 |
| Detection Limit (ng/mL) | 7,5 |
| Spike Recovery (%) | Between 85-115 |
| Shelf Life (year) | 1 |
| Assay type | Quantitative |
| Species Reactivity | Human |
| Storage conditions | Store at +4°C. Please refer to protocols. |
| Shipping conditions | At room temperature |
| # | File | Action |
|---|---|---|
| Safety Data Sheet (SDS) | Download |
Publications with this drug
| # | File | Action |
|---|---|---|
| Mocenigo, Marco, et al. "Rapid, cost-effective peptide/nucleic acid-based platform for therapeutic antibody monitoring in clinical samples." ACS sensors 5.10 (2020): 3109-3115. | Visit Link | |
| Padrón, Ivette Mourani, et al. "Anti-drug antibodies anti-trastuzumab in the treatment of breast cancer." Journal of Oncology Pharmacy Practice 27.6 (2021): 1354-1356. | Visit Link | |
| González García, Jonathan, et al. "Pharmacokinetics of trastuzumab after subcutaneous and intravenous administration in obese patients." Annals of Pharmacotherapy 54.8 (2020): 775-779. | Visit Link | |
| Puente‐Massaguer, Eduard, et al. "A statistical approach to improve compound screening in cell culture media." Engineering in life sciences 19.4 (2019): 315-327. | Visit Link | |
| González-García, Jonathan, et al. "Long-term stability of trastuzumab in plasma and whole blood samples stored under different conditions." Farmacia Hospitalaria 43.2 (2019): 50-52. | Visit Link | |
| González García, Jonathan, et al. "Influence of anthropometric characteristics in patients with Her2-positive breast cancer on initial plasma concentrations of trastuzumab." Annals of Pharmacotherapy 51.11 (2017): 976-980. | Visit Link | |
| Iwamoto, Noriko, Akinobu Hamada, and Takashi Shimada. "Antibody drug quantitation in coexistence with anti-drug antibodies on nSMOL bioanalysis." Analytical biochemistry 540 (2018): 30-37. | Visit Link | |
| Chen, Jing, et al. "Tailor-making fluorescent hyaluronic acid microgels via combining microfluidics and photoclick chemistry for sustained and localized delivery of herceptin in tumors." ACS applied materials & interfaces 10.4 (2018): 3929-3937. | Visit Link | |
| Hollevoet, Kevin, et al. "Prolonged in vivo expression and anti-tumor response of DNA-based anti-HER2 antibodies." Oncotarget 9.17 (2018): 13623. | Visit Link | |
| González-García, J., et al. "Plasma levels of trastuzumab in gastric cancer: Case report." Journal of Oncology Pharmacy Practice 23.8 (2017): 635-637. | Visit Link | |
| Genetically modified micro-organ secreting antibody and methods of use Reem MiariNir ShapirInbal ZAFIR-LAVIE | Visit Link | |
| Hollevoet, Kevin, et al. "Bridging the clinical gap for DNA-based antibody therapy through translational studies in sheep." Human Gene Therapy 30.11 (2019): 1431-1443. | Visit Link | |
| Nanoparticle and Macromolecular Transfer across the Human Placental Barrier | Download | |
| Iwamoto, Noriko, and Takashi Shimada. "Method for quantifying monoclonal antibody having antigen or anti-antibody bonded thereto." U.S. Patent No. 11,619,616. 4 Apr. 2023. | Visit Link | |
| Zhou, Xiaofeng, et al. "Novel human single-domain antibodies exert potent anti-tumor activity by targeting EGF-like repeat epitope of EpCAM." Frontiers in Pharmacology 16 (2025): 1530268. | Visit Link |
