Shikari® (S-ATT) Anti-Trastuzumab ELISA w/confirmation
TRA-QNS-HH
Enzyme immunoassay for the quantitative determination of antibodies to Trastuzumab (Herceptin®, Herclon®) in serum and plasma with confirmation.
This kit has been especially developed for the quantitative antibodies to Trastuzumab in serum and plasma samples
Trastuzumab (Herceptin®, Herclon®)was associated to the development of anti-trastuzumab antibodies, even some were reported to be neutralizing, in various percentages of patients during therapy with the drug (Herceptin®, Herclon®). This might lead to severe complications. This kit can be efficiently used for monitoring anti- trastuzumab antibodies during therapy and offers the clinician a tool for decision on possible preventive measures such as possible addition of immunosuppressive drug to reduce anti-trastuzumab antibodies.
All SHIKARI® ELISA kits are suitable for biosimilar work.
All SHIKARI® ELISA kits are produced under ISO 13485 quality system and have CE IVD mark.
For technical inquiry, please contact techsupport@matriksbiotek.com
| Required Volume (µl) | 20 |
| Total Time (min) | 140 |
| Sample | Serum, plasma |
| Sample Number | 96 |
| Detection Limit (ng/mL) | 7,5 |
| Spike Recovery (%) | Between 85-115 |
| Shelf Life (year) | 1 |
| Assay type | Quantitative |
| Species Reactivity | Human |
| Storage conditions | Store at +4°C. Please refer to protocols. |
| Shipping conditions | At room temperature |
| # | File | Action |
|---|---|---|
| Instructions For Use | Download | |
| Safety Data Sheet (SDS) | Download | |
| Validation Report | Download |
Publications with this drug
| # | File | Action |
|---|---|---|
| Mocenigo, Marco, et al. "Rapid, Cost-Effective Peptide/Nucleic Acid-Based Platform for Therapeutic Antibody Monitoring in Clinical Samples." ACS sensors 5.10 (2020): 3109-3115. | Visit Link | |
| Padrón, Ivette Mourani, et al. "Anti-drug antibodies anti-trastuzumab in the treatment of breast cancer." Journal of Oncology Pharmacy Practice (2020): 1078155220953873. | Visit Link | |
| González García, Jonathan, et al. "Pharmacokinetics of Trastuzumab After Subcutaneous and Intravenous Administration in Obese Patients." Annals of Pharmacotherapy (2020): 1060028020902318. | Visit Link | |
| Puente‐Massaguer, Eduard, et al. "A statistical approach to improve compound screening in cell culture media." Engineering in Life Sciences 19.4 (2019): 315-327. | Visit Link | |
| González-García, J., et al. "Long-term stability of trastuzumab in plasma and whole blood samples stored under different conditions." Farmacia hospitalaria: organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 43.2 (2019): 50-52. | Visit Link | |
| González García, Jonathan, et al. "Influence of anthropometric characteristics in patients with Her2-positive breast cancer on initial plasma concentrations of trastuzumab." Annals of Pharmacotherapy 51.11 (2017): 976-980. | Visit Link | |
| Iwamoto, Noriko, Akinobu Hamada, and Takashi Shimada. "Antibody drug quantitation in coexistence with anti-drug antibodies on nSMOL bioanalysis." Analytical biochemistry 540 (2018): 30-37. | Visit Link | |
| Jing Chen et. al., "Tailor-Making Fluorescent Hyaluronic Acid Microgels via Combining Microfluidics and Photoclick Chemistry for Sustained and Localized Delivery of Herceptin in Tumor." ACS Appl. Mater. Interfaces, (2018). | Visit Link | |
| Kevin H, et al, “Prolonged in vivo expression and anti-tumor response of DNA-based anti-HER2 antibodies”: Oncotarget, 2018, Vol. 9, (No. 17), pp: 13623-13636. | Visit Link | |
| Jonathan GG, Beatriz AÁ, Nazco C GJ, Norberto BL, Fernando GN. Plasma levels of trastuzumab in gastric cancer: Case report. J Oncol Pharm Pract. Sep 23, 2016. | Visit Link | |
| Genetically modified micro-organ secreting antibody and methods of use Reem MiariNir ShapirInbal ZAFIR-LAVIE | Visit Link | |
| Hollevoet, Kevin, et al. "Bridging the clinical gap for DNA-based antibody therapy through translational studies in sheep." Human Gene Therapy 30.11 (2019): 1431-1443. | Visit Link | |
| Nanoparticle and Macromolecular Transfer across the Human Placental Barrier | Download | |
| METHOD FOR QUANTIFYING MONOCLONAL ANTIBODY HAVIN ANTIGEN OR ANTI - ANTIBODY BONDED THERETO, Iwamoto et al. | Visit Link |