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Shikari®  (S-ATD) Anti-Denosumab ELISA w/confirmation

Enzyme immunoassay for the quantitative determination of antibodies to denosumab (Prolia®) in serum and plasma with confirmation.

This kit has been especially developed for the quantitative antibodies to denosumab in serum and plasma samples.

Denosumab (Prolia®) was associated to the development of anti-denosumab antibodies, even some were reported to be neutralizing, in various percentages of patients during therapy with the drug Prolia®. This might lead to severe complications. This kit can be efficiently used for monitoring anti-Denosuman antibodies during therapy and offers the clinician a tool for decision on possible preventive measures such as possible addition of immunosuppressive drug to reduce anti-Denosumab antibodies..

All SHIKARI® ELISA kits are suitable for biosimilar work.

All SHIKARI® ELISA kits are produced under ISO 13485 quality system.

Research Use Only (RUO)

For technical inquiry, IFU and other relevant documents please contact techsupport@matriksbiotek.com

 

Required Volume (µl) 5
Total Time (min) 140
Sample Serum, plasma
Sample Number 96
Detection Limit (ng/mL) 18,75
Spike Recovery (%) Between 85-115
Shelf Life (year) 1
Assay type Quantitative
Species Reactivity Human
Storage conditions Store at +4°C. Please refer to protocols.
Shipping conditions At room temperature
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Safety Data Sheet (SDS) Download

Publications with this drug

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Nanoparticle and Macromolecular Transfer across the Human Placental Barrier Download
Rahman, Mohammed Tanjimur, et al. "Nanoparticle-mediated synergistic drug combination for treating bone metastasis." Journal of Controlled Release 357 (2023): 498-510. Visit Link
Peterlin, Anton AN, et al. "Rethinking Bacterial Osteolysis: Translational Evidence From a Porcine Model and Fracture‐Related Infections." APMIS 134.2 (2026): e70151. Visit Link