Offer Request Form

Order list is empty

Shikari® (Q-RAV) Ravulizumab ELISA

Enzyme immunoassay for the quantitative determination of Ravulizumab (Ultomiris®) in human serum and plasma

This kit has been especially developed for the quantitative determination of Ravulizumab in serum and plasma samples between the Cmin and Cmax range of concentrations.

Ravulizumab Drug Bank Accession Number is DB11580

Ravulizumab is a potent and selective complement 5 (C5) inhibitor. It is a humanized monoclonal IgG2/4 kappa antibody produced in Chinese hamster ovary (CHO) cells. Ravulizumab was engineered from eculizumab, another complement inhibitor, to increase the duration of action and reduce the frequency of drug administration. It works by blocking terminal complement-mediated inflammation, cell activation, and cell lysis in blood disorders associated with the destruction of red blood cells, thrombosis, and impaired bone marrow function. Complement system activation plays an important role in innate and acquired immunity.
 Measurement of biological drug trough levels and antibody to biological drug gained high importance during the course of treatment. These measurements enable dose adjustments and switch to another class of biological drug when necessary.

All SHIKARI® ELISA kits are suitable for biosimilar work.

All SHIKARI® ELISA kits are produced under ISO 13485 quality system and have CE IVD mark.

For technical inquiry, please contact techsupport@matriksbiotek.com

Required Volume (µl) 10
Total Time (min) 70
Sample Serum, plasma
Sample Number 96
Detection Limit (ng/mL) 18,75
Spike Recovery (%) Between 85-115
Shelf Life (month) 6
Assay type Quantitative
Species Reactivity Human
Storage conditions Store at +4°C. Please refer to protocols.
Shipping conditions At room temperature
# File Action
Instructions for Use Download
SDS Download
Validation Report Download

Publications with this drug

# File Action